Dr. A. Karolina PALUCKA (2006)
A. Karolina Palucka MD PhD is at the Baylor Institute
for Immunology Research (BIIR) in Dallas. The Institute
aims to manipulate the human immune system for therapeutic
benefit in cancer, infectious and autoimmune diseases,
and transplantation. Dr. Palucka earned her medical
degree from Warsaw Medical Academy, where she focused
on internal medicine and oncology. Her desire was to
develop therapies for cancer but she says that she became
frustrated when she realized gthe lack of truly effective
therapies based on chemotherapy or radiotherapyh. Dr.
Paluckafs interests turned to immunology and using the
bodyfs immune system to fight cancer.
This interest led her to the Karolinska Institute in
Stockholm, where she obtained a Ph.D. in Hematology
and Immunology. After a postdoctoral fellowship in France
studying how cytokines regulate the differentiation
of monocytes into dendritic cells, Dr. Palucka joined
Baylor Institute for Immunology Research in 1998.
Dr. Palucka and her team focus on the use of dendritic
cells as vectors for cancer therapy. In this context,
she is leading the vaccine production facility and the
clinical trials program. She also leads a project to
develop a mouse model of the human immune system to
study human tumors and dendritic cell function. These
ehumanizedf mice are being used to develop improved
vaccine strategies and to improve our understanding
of how cancers evade the immune system.
She holds the Michael A.E. Ramsay Chair for Cancer